CDK9/CDC2L4 Protein Overview: Sequence, Structure, Function and Protein Interaction

CDK9/CDC2L4 Protein Overview

Positive transcription factor b (P-TEFb) controls the elongation phase of transcription by RNA polymerase II (see POLR2A; 180660). P-TEFb is a heterodimer of CDK9 and 1 of 4 cyclin partners, cyclin T1 (CCNT1; 143055), cyclin K (CCNK; 603544), or cyclin T2a or T2b, which are isoforms of CCNT2 (603862) (Shore et al., 2003).

CDK9/CDC2L4 protein family

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

CDK9/CDC2L4 protein name

Recommended name
Cyclin-dependent kinase 9

CDK9/CDC2L4 Gene family protein

CDK9/CDC2L4 Protein Molecular Weight & PI

The parameters have been computed for the following feature

FT CHAIN 1-372 Cyclin-dependent kinase 9.

Molecular weight (Da)


Theoretical pI


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