EGFL6 Gene Sequence, Family, Fuction and Expression Information

EGFL6 cDNA / Gene Overview

EGFL6 gene / cDNA is a protein-coding gene which located on Xp22.2. The EGFL6 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.225 organisms have orthologs with human gene EGFL6.

EGFL6 cDNA / Gene Function

This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]

EGFL6 cDNA / Gene Sequence

LOCUS NM_015507 2445 bp mRNA linear PRI 24-JUN-2018
Homo sapiens EGF like domain multiple 6 (EGFL6), transcript variant 1, mRNA.

This sequence information is just for reference only.

EGFL6 cDNA / Gene Expression

Restricted expression toward placenta (RPKM 287.0)