EMAP-II/AIMP1 Information: EMAP-II/AIMP1 Protein, EMAP-II/AIMP1 Antibody and EMAP-II/AIMP1 Gene

EMAP-II/AIMP1 Protein

EMAP-II/AIMP1 protein function

Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PubMed:10358004). Binds tRNA. Possesses inflammatory cytokine activity (PubMed:11306575). Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation (By similarity). Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels (By similarity). Promotes dermal fibroblast proliferation and wound repair (PubMed:16472771). Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum (By similarity). Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PubMed:12237313). Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:11818442). Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PubMed:19362550). {ECO:0000250|UniProtKB:P31230, ECO:0000269|PubMed:10358004, ECO:0000269|PubMed:11157763, ECO:0000269|PubMed:11306575, ECO:0000269|PubMed:11818442, ECO:0000269|PubMed:12237313, ECO:0000269|PubMed:19362550}.

EMAP-II/AIMP1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    312.00
  • Mass (KDa)
    34.00

EMAP-II/AIMP1 Antibody

There are 5 EMAP-II/AIMP1 antibodies which are validated in multiple tissues with various applications, including IHC-P, ELISA, WB, ICC/IF, IP. There are 3 EMAP-II/AIMP1 antibody for IHC-P, 4 EMAP-II/AIMP1 antibody for ELISA, 2 EMAP-II/AIMP1 antibody for WB, 1 EMAP-II/AIMP1 antibody for ICC/IF, 2 EMAP-II/AIMP1 antibody for IP. Among all these EMAP-II/AIMP1 antibodies, there are 1 anti-EMAP-II/AIMP1 mouse monoclonal antibodies , 4 anti-EMAP-II/AIMP1 rabbit polyclonal antibodies . All the EMAP-II/AIMP1 anbodies are produced in house and all are in stock. EMAP-II/AIMP1 antibody customerized service is available.

EMAP-II/AIMP1 Gene

AIMP1 gene / cDNA is a protein-coding gene which located on 4q24. The AIMP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, and frog.237 organisms have orthologs with human gene AIMP1.