EMR2 Information: EMR2 Protein, EMR2 Antibody and EMR2 Gene

EMR2 Gene family

EMR2 Protein

EMR2 protein function

Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242).

EMR2 protein expression

Tissue specificity

Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested. High expression in mast cells (PubMed:26841242).

EMR2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    823.00
  • Mass (KDa)
    90.00

EMR2 Antibody

There are 1 EMR2 antibodies which are validated in multiple tissues with various applications, including WB. There are 1 EMR2 antibody for WB. Among all these EMR2 antibodies, there are 1 anti-EMR2 rabbit polyclonal antibodies . All the EMR2 anbodies are produced in house and all are in stock. EMR2 antibody customerized service is available.

EMR2 Gene

ADGRE2 cDNA / gene is a gene with protein product which located on 19p13.12. The ADGRE2 gene is conserved in chimpanzee, Rhesus monkey, and dog. 44 organisms have orthologs with human gene ADGRE2.