FGF12 Information: FGF12 Protein, FGF12 Antibody and FGF12 Gene

FGF12 Protein

FGF12 protein function

Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. {ECO:0000269|PubMed:27164707}.

FGF12 protein expression

Tissue specificity

Brain, eye and testis; highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and in a segmental pattern of the body wall; in adult olfactory bulb, less in cerebellum, deep cerebellar nuclei, cortex and multiple midbrain structures.

FGF12 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

FGF12 Gene

FGF12 gene / cDNA is a protein-coding gene which located on 3q28-q29. The FGF12 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, and frog.198 organisms have orthologs with human gene FGF12.