G-CSF Gene Sequence, Family, Fuction and Expression Information

G-CSF cDNA / Gene Overview

CSF3 gene / cDNA is a protein-coding gene which located on 17q21.1. The CSF3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.155 organisms have orthologs with human gene CSF3.

G-CSF cDNA / Gene Function

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]

G-CSF cDNA / Gene Sequence

LOCUS
LOCUS NM_172220 1494 bp mRNA linear PRI 15-JUL-2018
DEFINITION
Homo sapiens colony stimulating factor 3 (CSF3), transcript variant 3, mRNA.
ACCESSION
NM_172220
VERSION
NM_172220.2

This sequence information is just for reference only.

G-CSF Family & Reagents

Gene family

G-CSF Gene family reagents (Endogenous ligands)

Approved Symbol Reagent list
THPO
MLN
BMP4
CCL27
MMP1
CXCL12
C3
EPO
CXCL1
GH1
Approved Symbol Reagent list
RSPO3
CCL3
VCAM1
CCL23
INHBA
FASLG
RSPO2
Spp1
CCL19
FN1

G-CSF cDNA / Gene Alias

  • filgrastim
  • granulocyte colony stimulating factor
  • lenograstim
  • MGC45931
  • pluripoietin

G-CSF cDNA / Gene Expression

Biased expression in appendix (RPKM 6.9), urinary bladder (RPKM 3.3) and 8 other tissues

Recombinant G-CSF protein citations

Title
Purification of target proteins from intracellular inclusions mediated by intein cleavable polyhydroxyalkanoate synthase fusions
Year
2017
Author
Du, J;Rehm, BHA;
Journal
Microb. Cell Fact.