HDAC1 Gene Sequence, Family, Fuction and Expression Information
HDAC1 cDNA / Gene Overview
HDAC1 gene / cDNA is a protein-coding gene which located on 1p35.2-p35.1. The HDAC1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.205 organisms have orthologs with human gene HDAC1.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
HDAC1 cDNA / Gene Sequence
LOCUS NM_004964 2091 bp mRNA linear PRI 03-JUN-2018
Homo sapiens histone deacetylase 1 (HDAC1), mRNA.
This sequence information is just for reference only.