HDAC1 Gene Sequence, Family, Fuction and Expression Information

HDAC1 cDNA / Gene Overview

HDAC1 gene / cDNA is a protein-coding gene which located on 1p35.2-p35.1. The HDAC1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.205 organisms have orthologs with human gene HDAC1.

HDAC1 cDNA / Gene Function

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]

HDAC1 cDNA / Gene Sequence

LOCUS
LOCUS NM_004964 2091 bp mRNA linear PRI 03-JUN-2018
DEFINITION
Homo sapiens histone deacetylase 1 (HDAC1), mRNA.
ACCESSION
NM_004964
VERSION
NM_004964.2

This sequence information is just for reference only.

HDAC1 Family & Reagents

HDAC1 Gene family reagents (Histone deacetylases, class I)

Approved Symbol Reagent list
HDAC3
Approved Symbol Reagent list
HDAC8

HDAC1 Gene family reagents (EMSY complex)

Approved Symbol Reagent list
RBBP4

HDAC1 Gene family reagents (NuRD complex)

Approved Symbol Reagent list
RBBP4

HDAC1 Gene family reagents (SIN3 histone deacetylase complex subunits)

Approved Symbol Reagent list
RBBP4

HDAC1 cDNA / Gene Alias

  • GON-10
  • HD1

HDAC1 cDNA / Gene Expression

Ubiquitous expression in lymph node (RPKM 56.9), colon (RPKM 56.3) and 25 other tissues