ICAM5 Gene Sequence, Family, Fuction and Expression Information
ICAM5 cDNA / Gene Overview
ICAM5 gene / cDNA is a protein-coding gene which located on 19p13.2. The ICAM5 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and frog.127 organisms have orthologs with human gene ICAM5.
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]
ICAM5 cDNA / Gene Sequence
LOCUS NM_003259 3005 bp mRNA linear PRI 24-JUN-2018
Homo sapiens intercellular adhesion molecule 5 (ICAM5), mRNA.
This sequence information is just for reference only.