LACE1 Information: LACE1 Protein, LACE1 Antibody and LACE1 Gene

LACE1 Protein

LACE1 protein function

Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain (PubMed:26759378, PubMed:27323408). Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress (PubMed:27323408).

LACE1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

LACE1 Gene

AFG1L cDNA / gene is a gene with protein product which located on 6q21. The AFG1L gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, N.crassa, A.thaliana, rice, and frog. 231 organisms have orthologs with human gene AFG1L.