MSX1 Gene Sequence, Family, Fuction and Expression Information

MSX1 cDNA / Gene Overview

MSX1 gene / cDNA is a protein-coding gene which located on 4p16.2. The MSX1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.215 organisms have orthologs with human gene MSX1.

MSX1 cDNA / Gene Function

This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008]

MSX1 cDNA / Gene Sequence

LOCUS
LOCUS NM_002448 1940 bp mRNA linear PRI 15-JUL-2018
DEFINITION
Homo sapiens msh homeobox 1 (MSX1), mRNA.
ACCESSION
NM_002448
VERSION
NM_002448.3

This sequence information is just for reference only.

MSX1 cDNA / Gene Alias

  • HYD1
  • OFC5

MSX1 cDNA / Gene Expression

Biased expression in endometrium (RPKM 10.8), fat (RPKM 4.4) and 8 other tissues