MTF1 Gene Sequence, Family, Fuction and Expression Information

MTF1 cDNA / Gene Overview

MTF1 cDNA / gene is a gene with protein product which located on 1p34.3. The MTF1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 241 organisms have orthologs with human gene MTF1.

MTF1 cDNA / Gene Function

This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008]

MTF1 cDNA / Gene Sequence

BC014454 2606 bp mRNA linear PRI 01-SEP-2006
Homo sapiens metal-regulatory transcription factor 1, mRNA (cDNA clone MGC:23036 IMAGE:4901099), complete cds.

This sequence information is just for reference only.

MTF1 cDNA / Gene Expression

Ubiquitous expression in bone marrow (RPKM 7.9), testis (RPKM 4.9) and 25 other tissues