MTF1 Gene Sequence, Family, Fuction and Expression Information
MTF1 cDNA / Gene Overview
MTF1 cDNA / gene is a gene with protein product which located on 1p34.3. The MTF1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. 241 organisms have orthologs with human gene MTF1.
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008]