NKp30/NCR3 Information: NKp30/NCR3 Protein, NKp30/NCR3 Antibody and NKp30/NCR3 Gene

NKp30/NCR3 Gene family

NKp30/NCR3 Protein

NKp30/NCR3 protein function

Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. {ECO:0000269|PubMed:10562324, ECO:0000269|PubMed:15784725, ECO:0000269|PubMed:18055229, ECO:0000269|PubMed:18852879}.

NKp30/NCR3 protein expression

Tissue specificity

Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.

NKp30/NCR3 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    201.00
  • Mass (KDa)
    21.00

NKp30/NCR3 Antibody

There are 4 NKp30/NCR3 antibodies which are validated in multiple tissues with various applications, including WB, ELISA. There are 1 NKp30/NCR3 antibody for WB, 4 NKp30/NCR3 antibody for ELISA. Among all these NKp30/NCR3 antibodies, there are 1 anti-NKp30/NCR3 rabbit monoclonal antibodies , 3 anti-NKp30/NCR3 rabbit polyclonal antibodies . All the NKp30/NCR3 anbodies are produced in house and all are in stock. NKp30/NCR3 antibody customerized service is available.

NKp30/NCR3 Gene

NCR3 gene / cDNA is a protein-coding gene which located on 6p21.33. The NCR3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, and rat.105 organisms have orthologs with human gene NCR3.