VCAM1 Information: VCAM1 Protein, VCAM1 Antibody and VCAM1 Gene

VCAM1 Gene family

VCAM1 Protein

VCAM1 protein function

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

VCAM1 protein expression

Tissue specificity

Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.

Induction

By cytokines (e.g. IL-1, TNF-alpha).

VCAM1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    739.00
  • Mass (KDa)
    81.00

VCAM1 Antibody

There are 22 VCAM1 antibodies which are validated in multiple tissues with various applications, including WB, ICC/IF, IP, ELISA(Cap), ELISA, ELISA(Det), IHC-P, FCM. There are 3 VCAM1 antibody for WB, 1 VCAM1 antibody for ICC/IF, 1 VCAM1 antibody for IP, 1 VCAM1 antibody for ELISA(Cap), 9 VCAM1 antibody for ELISA, 1 VCAM1 antibody for ELISA(Det), 3 VCAM1 antibody for IHC-P, 11 VCAM1 antibody for FCM. Among all these VCAM1 antibodies, there are 6 anti-VCAM1 rabbit polyclonal antibodies , 3 anti-VCAM1 mouse monoclonal antibodies , 13 anti-VCAM1 rabbit monoclonal antibodies . All the VCAM1 anbodies are produced in house and all are in stock. VCAM1 antibody customerized service is available.

VCAM1 Gene

VCAM1 gene / cDNA is a protein-coding gene which located on 1p21.2. The VCAM1 gene is conserved in Rhesus monkey, dog, cow, mouse, rat, and zebrafish.218 organisms have orthologs with human gene VCAM1.