Vimentin Protein Overview: Sequence, Structure, Function and Protein Interaction

Vimentin Protein Overview

Vimentin protein family

Belongs to the intermediate filament family.

Vimentin protein name

Recommended name
Vimentin

Vimentin Gene family protein

Vimentin Protein Sequence

Species Human Vimentin protein
Length 466
Mass (Da) 53652
Sequence Human Vimentin protein sequence
Species Mouse Vimentin protein
Length 466
Mass (Da) 53688
Sequence Mouse Vimentin protein sequence
Species Rat Vimentin protein
Length 466
Mass (Da) 53733
Sequence Rat Vimentin protein sequence

Vimentin Protein Molecular Weight & PI

Vimentin Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 2-466 Vimentin.

Molecular weight (Da)

53520.49

Theoretical pI

5.05

Vimentin Protein Structure

HUMAN VIMENTIN COIL 2B FRAGMENT (CYS2)
Deposited
2001-08-08   Released:  2002-03-15
Deposition Author(s)
Strelkov, S.V., Herrmann, H., Geisler, N., Zimbelmann, R., Aebi, U., Burkhard, P.
Organism(s)
Homo sapiens
Expression System
Escherichia coli BL21(DE3)
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.3000 Å
R-Value Free
0.262
R-Value Work
0.242
1GK4 From PDB

Human Vimentin protein Secondary structure

Vimentin Protein Interaction

Recombinant Vimentin Protein Feature

Vimentin Protein, Human, Recombinant (His Tag)

High Purity
> 95 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method

Recombinant Vimentin protein citations

Title
Extracellular vimentin modulates human dendritic cell activation
Year
2018
Author
Yu, MB;Guerra, J;Firek, A;Langridge, WHR;
Journal
Mol. Immunol.
Title
Click RNA for Rapid Capture and Identification of Intracellular MicroRNA Targets
Year
2019
Author
Zhang, P;Fu, H;Du, S;Wang, F;Yang, J;Cai, W;Liu, D;
Journal
Anal. Chem.
Title
Vimentin-targeting AIEgen-peptide conjugates: Wash-free fluorescence detection of EMT-type cancer cells and tissues
Year
2020
Author
Wei, H;Yu, Y;Wang, Y;Ying, Z;Cheng, W;Tian, X;Kan, Q;
Journal
Sensors and Actuators B: Chemical
Title
Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition
Year
2020
Author
Roy, S;Kapoor, A;Zhu, F;Mukhopadhyay, R;Ghosh, AK;Lee, H;Mazzone, J;Posner, GH;Arav-Boger, R;
Journal
J. Biol. Chem.

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